Steroids and derivatives
Medchemexpress LLC Ibuprofen-d3 | 121662-14-4 | 99.94% | C13H15D3O2 | 50 MG
Ibuprofen-d3 is a deuterium labeled Ibuprofen, acting as a COX-1 and COX-2 inhibitor with IC50s of 13 μM and 370 μM. It incorporates stable heavy isotopes, such as deuterium, into drug molecules as tracers for quantitation during drug development. This process has the potential to affect pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@H](CC[C@]4(C)[C@H]3CC[C@]12C)OC(=O)NCCCN(C)C | 5mg | 779524214](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502467785.JPG-250.jpg)
eMolecules 184582-91-0 | DMPAC-Chol | Broadpharm514.839 | C33H58N2O2 | 0.000 | CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@H](CC[C@]4(C)[C@H]3CC[C@]12C)OC(=O)NCCCN(C)C | 5mg | 779524214
DMPAC-Chol | Broadpharm | 184582-91-0514.839 | C33H58N2O2 | 0.000 | CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@H](CC[C@]4(C)[C@H]3CC[C@]12C)OC(=O)NCCCN(C)C | 5mg | 779524214
Medchemexpress LLC N-Caproicacid-d3 so 5mg
N-caproicacidsodiumsalt-d3 is the deuterium labeled N-caproicacidsodiumsalt[1]
Medchemexpress LLC Dopamine D2 receptor antagonist-1 | 1055411-77-2 | 99.1% | 1 ML
Dopamine D2 receptor antagonist-1 is a negative allosteric modulator (NAM) of the dopamine D2 receptor (D2R) with sub-mM affinity.
- Acts as a negative allosteric modulator
- Targets the dopamine D2 receptor (D2R)
- Exhibits sub-mM affinity
Cayman Chemical 6-MethylmercaptopurIn-d3 10mg
An internal standard for the quantification of 6-MMP by GC- or LC-MS
eMolecules 6147-11-1 | ??-mangostin | Ambeed | MFCD00135200 | 410.466 | C24H26O6 | 98.000 | COc1c(O)cc2oc3cc(O)c(CC=C(C)C)c(O)c3c(=O)c2c1CC=C(C)C | 1mg | 761012452
??-mangostin | Ambeed | 6147-11-1 | MFCD00135200 | 410.466 | C24H26O6 | 98.000 | COc1c(O)cc2oc3cc(O)c(CC=C(C)C)c(O)c3c(=O)c2c1CC=C(C)C | 1mg | 761012452
Cambridge Isotope Laboratories 2 4-Dinitrotoluene (ring-D3 98%) 1 mg/mL in acetonitrile-D3 1 mL
2 4-Dinitrotoluene (ring-D3 98%) 1 mg/mL in acetonitrile-D3 1 mL
Medchemexpress LLC Betaine-d3 chloride | 1219349-47-9 | 156.63 | 1 MG
Betaine-d3 (chloride) is a deuterium-labeled version of Betaine chloride. It is intended for research use only and not for sale to patients. Stable heavy isotopes, such as deuterium, are incorporated into drug molecules primarily as tracers for quantitative analysis during drug development, and deuterium substitution can influence the pharmacokinetic and metabolic profiles of drugs.
- Deuterium labeled Betaine chloride.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Purity: 98.63%.
Medchemexpress LLC Ramelteon-d3 | 1432057-38-9 | 99.0% | C16H18D3NO2 | 1 MG
Ramelteon-d3 (TAK-375-d3) is a deuterium-labelled Ramelteon, a potent and highly selective agonist of MT1/MT2 receptors. It has potential for insomnia research, consistently reducing sleep onset without residual effects or withdrawal symptoms. This compound can be used as a tracer and as an internal standard for quantitative analysis, with deuteration potentially affecting pharmacokinetic and metabolic profiles of drugs.
- Deuterium-labelled Ramelteon
- Agonist of MT1/MT2 receptors
- Reduces sleep onset without residual effects
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Cayman Chemical HexnoIc AcId-d3 250mg
An internal standard for the quantification of hexanoic acid by GC- or LC-MS
Medchemexpress LLC Cortodoxone-d2 | 1271728-08-5 | 99.0% | C21H28D2O4 | 1 MG
Cortodoxone-d2 is a deuterium labeled glucocorticoid steroid hormone that can be oxygenated to cortisol (Hydrocortisone). It is suitable for use as a tracer or an internal standard for quantitative analysis in various analytical techniques.
- Can be used as a tracer.
- Acts as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes as tracers for quantitation in drug development.
- Deuteration offers potential to affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC HY-10001 5mg Medchemexpress, Calcipotriol CAS:112965-21-6 Purity:>98%
Medchemexpress, HY-10001 5mg Calcipotriol CAS:112965-21-6 Calcipotriol is a synthetic VitD 3 analogue with a high affinity for the vitamin D receptor. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Dopamine D2 receptor agonist-3 | 1257326-24-1 | 98.3% | 295.81 | C15H22ClN3O | 5 MG
Dopamine D2 receptor agonist-3 is a small-molecule research compound that acts as a selective dopamine D2 receptor partial agonist and a dopamine D3 receptor antagonist, with reported in vitro potency and demonstrated brain penetration in vivo. It is supplied as a solid (white to off-white) with high stated purity for laboratory use.
- Selective D2 partial agonist and D3 antagonist activity.
- Potency reported as pEC50 D2 = 8.3; D3 < 5.5 (approx. D2 EC50 ≈ 5 nM).
- Demonstrated brain penetration (brain:blood ratio 5.5; Tmax 0.5 h at 3 mg/kg, s.c.).
- High purity (98.3%) suitable for research applications.
- Solid, white to off-white appearance, available in small research pack sizes.
[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C | 10mg | 722709657](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502479365.JPG-250.jpg)
eMolecules 54668-67-6 | CHOL-5-ENE-3-BETA,24-DIOL | AstaTech360.582 | C24H40O2 | 95.000 | C[C@H](CCCO)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C | 10mg | 722709657
CHOL-5-ENE-3-BETA,24-DIOL | AstaTech | 54668-67-6360.582 | C24H40O2 | 95.000 | C[C@H](CCCO)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C | 10mg | 722709657